The effect of irrigation and nutrient treatments on physical properties of safflower seeds was investigated. Physical properties of safflower seeds were determined at a moisture content of 7% w.b. The parameters determined at different treatments were: size, geometric mean diameter, sphericity, surface area, mass, volume, bulk and true densities, porosity, and static and dynamic coefficient of friction. The results showed a better effect of the use of organic fertilizers in comparison with chemical ones. The results showed that nutrient and irrigation treatments had a significant effect on most of the physical properties of safflower seeds at p<0.01.