A field experiment with winter wheat (Triticum aestivum) on Orthic Luvisol was conducted for a period of eleven years. This study gives the ground to establish correctly the fertilizer rates, especially nitrogen, in accordance with the moisture conditions of the year. Winter precipitation (October-March) plays an especially important role because of the fact that it coincides with the timing of early spring dressing and gives opportunity for more precise determination of the nitrogen fertilizer rates. It was established that application of nitrogen at 120 kg ha-1 was unprofitable when autumn-winter precipitation sums were below 250 mm. Nitrogen fertilizer rates of 180 kg ha-1 could be used only when autumn-winter precipitation exceeded 350 mm. In order to quantify the connection between meteorological conditions and fertilizer utilization efficiency, a statistical analysis was used.