The work is based on meteorological data recorded by nine stations of the Institute of Meteorology and Water Management located in east-central Poland from 1971 to 2005. The region encompasses the North Podlasian Lowland and the South Podlasian Lowland. Average values of selected agroclimate indicators for the growing season were determined. Moreover, principal component analysis was conducted to indicate elements that exerted the greatest influence on the agroclimate. Also, cluster analysis was carried out to select stations with similar agroclimate. Ward method was used for clustering and the Euclidean distance was applied. Principal component analysis revealed that the agroclimate of east-central Poland was predominantly affected by climatic water balance, number of days of active plant growth, length of the farming period, and the average air temperature during the growing season (Apr-Sept). Based on the analysis, the region of east-central Poland was divided into two groups (areas) with different agroclimatic conditions. The first area comprized the following stations: Szepietowo and Białowieża located in the North Podlasian Lowland and Biała Podlaska situated in the northern part of the South Podlasian Lowland. This area was characterized by shorter farming periods and a lower average air temperature during the growing season. The other group included the remaining stations located in the western part of both the Lowlands which was warmer and where greater water deficits were recorded.